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| Registros recuperados: 176 | |
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| Xia,H.; Ye,J.; Wang,L.; Zhu,J.; He,Z.. |
| Glutathione synthetase deficiency (GSSD) is a rare inborn error of glutathione metabolism with autosomal recessive inheritance. The severe form of the disease is characterized by acute metabolic acidosis, usually present in the neonatal period with hemolytic anemia and progressive encephalopathy. A case of a male newborn infant who had severe metabolic acidosis with high anion gap, hemolytic anemia, and hyperbilirubinemia is reported. A high level of 5-oxoproline was detected in his urine and a diagnosis of generalized GSSD was made. DNA sequence analysis revealed the infant to be compound heterozygous with two mutations, c.738dupG in exon 8 of GSS gene resulting in p.S247fs and a repetitive sequence in exon 3 of GSS gene. Treatment after diagnosis of GSSD... |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Glutathione synthetase; 5-oxoprolinuria; Newborn; Metabolism; Mutation. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000300501 |
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| Lopes,J.B.; Moreira,J.A.; Kebreab,E.; Vitti,D.M.S.S.; Abdalla,A.L.; Crompton,L.A.; France,J.. |
| Ten crossbred barrows weighting 20kg were allocated in five groups fed and on diets consisted of different total phosphorus (P) levels: 0.30%, 0.40%, 0.51%, 0.65%, and 0.73%. The animals were intravenously injected 7.4MBq of radioactive P (32P) and after seven days they were slaughtered for further analysis. The evaluated parameters were intake, excretion, specific activities, and flow of P in compartments (1-gut, 2-blood, 3-bone, and 4-soft tissue). Besides fecal losses, the kidneys played an import role in P regulation. The flows of P from tissue and gut to the blood were affected by P intake. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pig; Metabolism; Balance; True absorption; Radio-phosphorus; Kinetic. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352009000300024 |
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| Trevizan,Luiz Roberto P.; Baptista,Gilberto C. de; Papa,Geraldo. |
| Increasing horticultural production under protected cultivation requires more detailed studies about the occurence of pesticide residues, due to the special and peculiar environment under controlled conditions, in which some pests, that are of little concern in the field, become important. The insecticide acephate and its methamidophos metabolite residues were evaluated in greenhouse-grown tomatoes and compared to an open-field tomato crop. The treatments: (a) check; (b) one application of 75 g a.i. acephate.100 L-1 water; (c) one application of 150 g a.i.100 L-1 water; (d) four applications of 75 g a.i.100 L-1 water were evaluated. Fruit, leaf and soil samples were taken at (-1), zero, 1, 3, 7, 14, 21 days after the last or only application. The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lycopersicon esculentum; Pesticide residues; Metabolism; Greenhouse. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-05362005000100008 |
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| Long, Marc; Tallec, Kevin; Soudant, Philippe; Le Grand, Fabienne; Donval, Anne; Lambert, Christophe; Sarthou, Geraldine; Jolley, Dianne F.; Hegaret, Helene. |
| Allelochemical interactions are likely to be a contributing factor explaining the success of large blooms of the harmful marine dinoflagellate Alexandrium, however, the physiological mechanisms of allelochemical interactions remain poorly described. Here we investigated the sub-lethal effects (on an hourly scale) of a filtrate containing allelochemicals from Alexandrium minutum on the physiology of the common diatom Chaetoceros muelleri. The filtrate induced deleterious effects to the diatom physiology within only 30 min of exposure. Esterase activity and photosynthesis were drastically inhibited, with up to 34% of the population being metabolically inactive and up to 30% reduction in photosystem II quantum yield when exposed to the filtrate. In addition,... |
| Tipo: Text |
Palavras-chave: Allelopathy; Alexandrium; Metabolism; Photoinhibition; Lipids; Pigments. |
| Ano: 2018 |
URL: https://archimer.ifremer.fr/doc/00460/57133/59748.pdf |
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| Alves,Gutemberg G.; Marinho-Carvalho,Monica M.; Atella,Georgia C.; Silva-Neto,Mario A.C.; Sola-Penna,Mauro. |
| 6-phosphofructo-1-kinase (phosphofructokinase; PFK) activity from Rhodnius prolixus, a haematophagous insect which is usually a poor flyer, was measured and compared in two metabolically active tissues - flight muscle and fat body. The activity of this important regulatory glycolytic enzyme was much more pronounced in muscle (15.1 ± 1.4 U/mg) than in fat body extracts (3.6±0.4 U/mg), although the latter presented higher levels of enzyme per protein content, as measured by western-blotting. Muscle extracts are more responsible than fat body to ATP and fructose 6-phosphate, both substrates of PFK. Allosteric regulation exerted by different effectors such as ADP, AMP and fructose 2,6-phosphate presented a singular pattern for each tissue. Optimal pH (8.0-8.5)... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Phosphofructokinase; Metabolism; Insect. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652007000100008 |
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| Petit,Hélène V.. |
| This manuscript reports on the main problems decreasing productivity of dairy cows (e.g. fatty liver syndrome and poor fertility) and how antioxidants could enhance it. High producing dairy cows are prone to oxidative stress, and the situation can be exacerbated under certain environmental, physiological, and dietary conditions. Antioxidants have important effects on the expression of genes involved in the antioxidant status, which may enhance animal health and reproduction. Moreover, antioxidants may contribute to decrease the incidence of spontaneous oxidized flavour in milk enriched in polyunsaturated fatty acids. Plant lignans are strong antioxidants and flax is the richest source of plant lignans. Flax lignans are converted in the mammalian lignans... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant; Bovine; Flaxseed; Metabolism. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982009001300035 |
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| Chatelier, Aurelien; Mckenzie, David; Prinet, Aurelie; Galois, Robert; Robin, Jean; Zambonino, Jose-luis; Claireaux, Guy. |
| Seabass were fed for 4 months with diets where the lipid was provided as either canola oil (CO), palm oil ( PO) or fish oil (FO), to generate diversity in their tissue fatty acid (FA) composition and investigate how this influenced major traits of exercise performance, cardiac performance and respiratory metabolism. In particular, based upon previous observations, we investigated the hypothesis that enriching the fish tissues with oleic and linoleic acids (OA, 18:1n-9 and LA, 18:2n-6, respectively) from the CO and PO diets would improve maximum exercise and cardiac performance, and increase aerobic metabolic scope. This proved to be the case; exercise respirometry on bass fitted with cardiac flow probes revealed that those fed CO and PO diets had a... |
| Tipo: Text |
Palavras-chave: Diet; Fatty acid; Cardiovascular performance; Metabolism; Swimming; Dicentrarchus labrax; Seabass. |
| Ano: 2006 |
URL: http://archimer.ifremer.fr/doc/2006/publication-1860.pdf |
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| Gaudy, R; Youssara, F; Diaz, F; Raimbault, P. |
| Zooplankton biomass was measured at 20 stations located along five coastal-offshore transects in the Gulf of Lions (NW Mediterranean) during spring 1998 and winter 1999, using two nets equipped with 200 and 80 Pm mesh. Biomass was twice as abundant in spring. It increased toward the coast and the west of the gulf and was positively correlated to chlorophyll, primary production and organic particulate matter and negatively to temperature and salinity. The enrichment effect of Rhone river input and the oligotrophic influence of the north Mediterranean current (NMC) were the main distribution factors of zooplankton biomass. Higher biomass was obtained in coastal stations with the 80 mum net, which sampled more efficiently young larval stages and nauplii.... |
| Tipo: Text |
Palavras-chave: Zooplankton; Métabolisme; Cycle saisonnal; Golfe du Lion; Zooplankton; Metabolism; Seasonal cycle; Gulf of Lions. |
| Ano: 2003 |
URL: http://archimer.ifremer.fr/doc/00321/43262/42993.pdf |
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| Dube,Aman K.; Kumar,Maushmi S.. |
| Abstract Fungi is a well-known model used to study drug metabolism and its production in in vitro condition. We aim to screen the most efficient strain of Cunninghamella sp. among C. elegans, C. echinulata and C. blakesleeana for bromhexine metabolites production. We characterized the metabolites produced using various analytical tools and compared them with mammalian metabolites in Rat liver microsomes (RLM). The metabolites were collected by two-stage fermentation of bromhexine with different strains of Cunninghamella sp. followed by extraction. Analysis was done by thin layer chromatography, high performance thin layer chromatography, Fourier transform infrared spectroscopy, high performance liquid chromatography and Liquid chromatography–mass... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cunninghamella sp.; Bromhexine; RLM; CYP3A4; Inhibitor; Metabolism. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000200259 |
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| Carmo,Fabiana Bononi; Terreri,Maria Teresa; Succi,Regina Célia de Menezes; Beltrão,Suenia Vasconcelos; Gouvea,Aida de Fátima Tomé Barbosa; Paulino,Erica Regina Cruz; Machado,Daisy Maria. |
| ABSTRACT Background: The increase in life expectancy for patients living with human immunodeficiency virus (HIV) infection has resulted in health complications related to a chronic disease. Objectives: To evaluate the prevalence of bone mineral density (BMD) alterations and vitamin D concentrations in HIV-infected children and adolescents and to verify the variations in those parameters during a 12-month interval. Methods: A prospective cohort study with a dual period of evaluation was conducted in 57 patients perinatally HIV-infected and one patient with sexual abuse in early infancy. Demographic, anthropometric, pubertal stage, viral load, T CD4+ cell count and antiretroviral therapy were evaluated. Biochemical tests and total body (TB) and lumbar... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV; Antiretroviral; Infant; Diagnosis; Metabolism; Bone. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000300270 |
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| Rufino, João Paulo Ferreira; Cruz, Frank George Guimarães; Melo, Ramon Duque; Feijó, Julmar da Costa; Melo, Lucas Duque; Costa, Ana Paula Guimarães Cruz; Bezerra, Natalia dos Santos. |
| This study aimed to evaluate the inclusion of Brazil nut oil in diets for breeder cocks on performance, semen analyses, biochemical serum profile and testicular morphology. Forty-two Rhode Island Red breeder cocks with 40 weeks of age were used. The experimental design was completely randomized consisting of seven levels of Brazil nut oil (0; 0.30; 0.60; 0.90; 1.20; 1.50 and 1.80%) in the diets. Data collected were evaluated by polynomial regression. Differences (p < 0.05) were detected in feed conversion, semen volume, motility, vigor, pH, swirling and concentration, in which the inclusion of Brazil nut oil in the diets improved the reproductive performance. Differences (p < 0.05) were also detected in the biochemical serum profile (triglycerides,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Additive; Fatty acids; Metabolism; Reproductive performance.. |
| Ano: 2017 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/37472 |
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| Registros recuperados: 176 | |
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